Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
MT-2
A research compound studied in laboratory models involving melanocortin receptor pathway analysis and pigmentation biology research.
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Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
About MT-2
Melanotan II (MT-2) is a cyclic synthetic heptapeptide analog of α-MSH incorporating a lactam bridge between aspartic acid and lysine residues to constrain the peptide backbone into a pharmacologically active β-turn conformation. The molecule features an N-terminal norleucine residue for stability, a D-Phe residue at position 4 for enhanced MC receptor affinity (the His-D-Phe-Arg-Trp core constitutes the essential melanocortin pharmacophore), and a C-terminal hydroxyl rather than the amide found in bremelanotide (PT-141). MT-2 acts as a non-selective agonist across melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R.
Research applications of MT-2 include melanocortin receptor binding competition assays, comparative receptor selectivity studies relative to α-MSH and linear analogs, cAMP signaling pathway characterization in transfected cell lines, and investigation of MC4R activation dynamics in hypothalamic neuronal cell models. The rigid cyclic structure of MT-2 makes it a valuable tool in structure-activity relationship studies examining the conformational requirements of the melanocortin pharmacophore. For laboratory research use by qualified investigators only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic heptapeptide via Asp-Lys lactam bridge) |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | 1,024.2 g/mol |
| CAS Number | 121062-08-6 |
| PubChem CID | 5311071 |
| Synonyms | Melanotan II, Melanotan 2, MT-II |
Source: PubChem — for research reference only.
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
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Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
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GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
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Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
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Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
MT-2 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Pigmentation / Tanning
Purity
≥98.0%
Available Sizes
10MG
COA
Available