Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
MOTS-c
A research compound studied in laboratory models involving mitochondrial signaling, cellular stress response, and biological pathway investigation.
Select Size / Specification
Selected: 10mg x 10vials
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Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Pricing & Specifications
| Specification | Strength | Pack | Total Qty | 1 Vial | 3 Vial Bundle | 10 Vial Kit | Kit Savings |
|---|---|---|---|---|---|---|---|
| 10mg x 10vials | 10 MG | 10 | 100 MG | $95.00 | $270.75 | $712.5025% off | $237.50 |
| 40mg x 10vials | 40 MG | 10 | 400 MG | $315.00 | $897.75 | $2,362.5025% off | $787.50 |
About MOTS-c
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA, type c) is a 16-amino acid peptide encoded by a short open reading frame (sORF) within the mitochondrial 12S ribosomal RNA gene. Discovered in 2015, MOTS-c is translated in the mitochondrial matrix using the standard mitochondrial genetic code and subsequently exported to the cytoplasm and nucleus. It represents one of the first described mitochondrial-derived peptides (MDPs) — a class of small regulatory peptides encoded entirely within the mitochondrial genome.
Research interest in MOTS-c has focused on its translocation from the cytoplasm to the nucleus in response to metabolic stress, where it has been shown to interact with nuclear transcription factor binding sites including ARE (antioxidant response elements). In vitro studies have characterized its effects on AMPK pathway activation, glucose metabolism regulation in skeletal muscle cell models, and oxidative stress response pathway modulation. MOTS-c is considered an important research tool for studying mitochondrial-nuclear communication mechanisms. For laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Formula | C99H173N35O27 |
| Molecular Weight | 2,174.7 g/mol |
| CAS Number | 1627580-50-0 |
| Synonyms | Mitochondrial ORF of the 12S rRNA type-c, MOTS-c peptide, Humanin-related peptide |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
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SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
MOTS-c is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Mitochondrial / Longevity
Purity
≥98.0%
Available Sizes
10MG, 40MG
COA
Available