Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
IGF-1LR3
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
Select Size / Specification
Selected: 0.1mg x 10vials
Choose Pack Size
Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Pricing & Specifications
| Specification | Strength | Pack | Total Qty | 1 Vial | 3 Vial Bundle | 10 Vial Kit | Kit Savings |
|---|---|---|---|---|---|---|---|
| 0.1mg x 10vials | 0.1 MG | 10 | 1 MG | $28.00 | $79.80 | $210.0025% off | $70.00 |
| 1mg x 10vials | 1 MG | 10 | 10 MG | $34.00 | $96.90 | $255.0025% off | $85.00 |
About IGF-1LR3
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a recombinant analog of human IGF-1 in which an N-terminal 13-amino acid extension (MFPAMPLLSLFVNG) is added and the glutamic acid at position 3 of native IGF-1 is substituted with arginine. These modifications profoundly reduce the peptide's binding affinity for all six IGF binding proteins (IGFBP-1 through IGFBP-6) — particularly IGFBP-3 — by approximately 2,000-fold, while maintaining high agonist affinity at the IGF-1 receptor (IGF-1R). The result is a significantly more potent in vitro growth factor due to the near-elimination of IGFBP-mediated buffering.
IGF-1 LR3 is widely used as a research tool in cell culture systems where native IGF-1 bioavailability is limited by endogenous IGFBPs present in serum-containing media. Research applications include IGF-1R signaling pathway characterization (IRS-1/PI3K/Akt, Ras/MAPK), comparative IGF-1R binding kinetics studies, cell proliferation assay standardization, and investigation of IGF-axis independent of IGFBP interference in defined in vitro settings. For qualified laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | MFPAMPLLSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA... (83 AA Long Arg3 N-terminal extension + 70 AA IGF-1 sequence) |
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight | 9,117.6 g/mol |
| CAS Number | 946870-92-4 |
| Synonyms | Long Arg3 IGF-1, LR3-IGF-1, Insulin-like Growth Factor-1 Long R3, IGF-1 LR3 |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
FAST
SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
IGF-1LR3 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
0.1MG, 1MG
COA
Available