Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
5-Amino-1MQ
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
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Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
About 5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small heterocyclic compound that functions as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for catalyzing the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, forming 1-methylnicotinamide (MNA). By inhibiting NNMT, 5-amino-1MQ prevents the consumption of SAM methyl groups in this pathway, thereby increasing the availability of SAM-derived methyl donors for other methylation reactions and potentially elevating cellular NAD+ precursor pools in experimental models.
Research applications of 5-amino-1MQ encompass NNMT enzyme inhibition kinetics and IC₅₀ determination studies, SAM/SAH ratio modulation in cell culture models, NAD+ metabolome characterization, and investigation of NNMT's role in adipocyte metabolism, one-carbon metabolism flux, and epigenetic methylation regulation. The compound is a frequently used probe in NNMT biology research and is of scientific interest as a tool for studying metabolic reprogramming in cellular models. This product is intended for qualified laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Not applicable — small molecule heterocyclic compound |
| Molecular Formula | C7H9N3 |
| Molecular Weight | 135.17 g/mol |
| CAS Number | 1379592-28-9 |
| Synonyms | 5-Amino-1-methylquinolinium, 5-A1MQ, NNMT inhibitor, 1-Methyl-5-aminoquinolinium |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
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Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
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Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
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Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
5-Amino-1MQ is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
5MG
COA
Available